Bastián, after the surprising resolution of the challenge on the enigmatic signature of Christopher Columbus, is invited by the company Think ('Think') to participate in the world conference on Leonardo da Vinci sponsors in Madrid. The initial objective is to discuss the meaning of the symbolic Renaissance painting entitled Portrait of Luca Pacioli and his disciple. Luca Pacioli was a friar friend, and teacher of mathematics, of Leonardo da Vinci at the Court of Milan.

   The final result of the world conference on Leonardo, after the concatenation of discoveries that Bastián will explain in a marvelous way, leads us to a greater mystery.